What is the Origin of Epigenetic Age Deceleration?

This term is derived from "Epigenetics," the study of heritable phenotype changes not involving alterations in the DNA sequence, combined with "Age Deceleration," reflecting empirical data showing shifts in biological aging markers toward a younger state. It connects lifestyle and hormonal factors directly to genomic expression stability.

What is the Mechanism of Epigenetic Age Deceleration?

Deceleration often involves modulating the activity of specific enzymes, such as DNA methyltransferases or histone deacetylases, which control chromatin accessibility across the genome. Optimal endocrine signaling, particularly involving sex hormones and insulin-like growth factors, supports the necessary enzymatic balance to maintain a more youthful pattern of DNA methylation marks associated with healthy tissue function.

Epigenetic Age Deceleration

Meaning

Epigenetic Age Deceleration is the measurable slowing or reversal of biological aging as quantified by epigenetic clocks, such as DNA methylation patterns, often correlated with interventions that optimize the hormonal milieu and cellular environment. It suggests a functional rejuvenation trajectory extending beyond mere chronological time measurement.