Question 1

What is the Meaning of Epididymis?

Accepted Answer

The Epididymis is a long, coiled duct that connects the efferent ducts of the testis to the vas deferens in the male reproductive system. This highly specialized, androgen-dependent organ is physiologically essential for the post-testicular maturation, concentration, and storage of spermatozoa. Its environment is meticulously regulated to allow sperm to acquire the necessary motility and fertilizing capacity required for successful reproduction.

Question 2

What is the Origin of Epididymis?

Accepted Answer

The term originates from the Greek words epi, meaning 'upon,' and didymos, meaning 'testis,' literally translating to 'upon the testis,' describing its anatomical location. As a key component of the male reproductive tract, its function has been recognized since the earliest studies of human and mammalian anatomy. In endocrinology, its significance lies in its dependence on androgenic hormones for structural and functional maintenance.

Question 3

What is the Mechanism of Epididymis?

Accepted Answer

The mechanism of function is largely regulated by androgens, primarily testosterone and its more potent metabolite, dihydrotestosterone, which maintain the epithelial cell structure and secretory activity. These epithelial cells actively modify the luminal fluid composition by absorption and secretion of specific proteins and small molecules. This androgen-regulated microenvironment facilitates the biochemical and morphological changes in sperm, collectively known as sperm maturation, including the acquisition of forward motility.

Epididymis

Meaning

Origin

Mechanism

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