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Enzyme Induction

Meaning

Enzyme induction is a biochemical process where the rate of synthesis or activity of a specific enzyme is increased, typically in response to exposure to an external substance, known as an inducer. In the context of hormonal health, this often pertains to the hepatic cytochrome P450 enzyme system, which is crucial for the metabolism and clearance of steroid hormones and xenobiotics. Enhanced enzyme activity can lead to faster breakdown of hormones or medications, potentially altering their therapeutic effect or biological half-life. Clinical monitoring is essential when managing patients exposed to known enzyme inducers to prevent sub-therapeutic hormone levels.