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Environmental Modulators

Meaning

Environmental Modulators are external, non-genetic factors—including dietary composition, sleep hygiene, artificial light exposure, physical activity patterns, and exposure to specific endocrine-disrupting chemicals—that exert a profound and measurable influence on the body’s physiological and hormonal systems. They function as potent, dynamic regulators of gene expression and intricate endocrine signaling pathways, often determining whether a genetic predisposition manifests as a clinical phenotype. Recognizing and manipulating these modulators is central to lifestyle medicine and personalized wellness, as they offer a primary, non-pharmacological pathway for optimizing health and longevity.