Question 1

What is the Meaning of Entorhinal Cortex?

Accepted Answer

A critical hub region of the cerebral cortex located in the medial temporal lobe, serving as the main interface between the neocortex and the hippocampus. This brain structure is essential for memory formation, spatial navigation, and the initial processing of sensory information destined for long-term storage. It is anatomically crucial for declarative memory.

Question 2

What is the Origin of Entorhinal Cortex?

Accepted Answer

The name derives from the Greek entos (within) and rhinos (nose), reflecting its deep location and early recognition as part of the olfactory system. Its primary modern significance, however, lies in cognitive neuroscience and memory research. This region is a well-studied and highly vulnerable area in the context of neurodegenerative diseases, such as Alzheimer's disease.

Question 3

What is the Mechanism of Entorhinal Cortex?

Accepted Answer

The Entorhinal Cortex functions as a gateway, receiving highly processed input from various cortical association areas and relaying it to the hippocampus via the perforant path, a crucial pathway for episodic memory encoding. Its layer II neurons are particularly involved in generating grid cells and border cells, which form a spatial coordinate system vital for navigation. The structural integrity of this region is paramount for translating short-term sensory experience into enduring memory traces.

Entorhinal Cortex

Meaning

Origin

Mechanism

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