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Enteroendocrine Function

Meaning

Enteroendocrine Function describes the crucial signaling role of specialized cells scattered throughout the gastrointestinal tract lining, which act as a diffuse endocrine organ. These enteroendocrine cells (EECs) sense the luminal contents, such as nutrients and microbial metabolites, and respond by secreting a diverse array of peptide hormones. These hormones, including GLP-1, ghrelin, and cholecystokinin (CCK), are vital regulators of appetite, glucose homeostasis, digestion, and gut motility. This function represents a direct communication link between the gut environment and systemic metabolism.