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Enteroendocrine

Meaning

Enteroendocrine is an adjective used to describe specialized cells, tissues, or functions related to the endocrine activity originating within the enteric (gastrointestinal) system. These cells, dispersed throughout the gut epithelium, function as chemosensors, detecting the presence of nutrients, toxins, and microbes within the gut lumen. Upon stimulation, they secrete a diverse array of peptide hormones directly into the bloodstream or the surrounding tissue, acting as key regulators of digestion, appetite, glucose homeostasis, and gut motility. Their crucial role bridges the digestive and endocrine systems, profoundly impacting metabolic health.