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Energy Source Potency

Meaning

Energy source potency, in a physiological context, quantifies the relative efficiency and sustained capacity of various metabolic substrates—primarily glucose, fatty acids, and ketones—to generate Adenosine Triphosphate (ATP), the universal cellular energy currency. This metric is critical in endocrinology, as it reflects the efficiency of hormonal signaling, particularly insulin and thyroid hormones, in regulating fuel partitioning and mitochondrial function. A high potency indicates efficient substrate utilization, contributing to enhanced physical endurance and cognitive function, while diminished potency often signals metabolic dysfunction like insulin resistance. Understanding this metric guides nutritional and therapeutic strategies for optimizing human performance.