Energy Resource Mobilization is the acute physiological process by which the body rapidly converts stored energy substrates, primarily glycogen and triglycerides, into readily usable forms like glucose and free fatty acids. This mechanism is fundamentally regulated by counter-regulatory hormones, such as glucagon, epinephrine, and cortisol, in response to energy demands, stress, or fasting. Effective mobilization ensures a sustained supply of fuel for muscular and cognitive function, which is critical for maintaining performance.
Origin
This term originates from classical human physiology and endocrinology, describing the metabolic processes essential for energy homeostasis. It reflects the body’s adaptive, survival-oriented strategy to transition from a fed state of storage to a fasting or active state of fuel utilization. The pathways involved are deeply rooted in the evolutionary need for rapid energy access during times of scarcity or threat.
Mechanism
Hormones like epinephrine initiate lipolysis in adipose tissue and glycogenolysis in the liver and muscle by binding to specific receptors, activating downstream signaling cascades. This cascade leads to the phosphorylation and activation of key enzymes, such as hormone-sensitive lipase and glycogen phosphorylase. The resulting glucose and fatty acids are then released into the circulation for uptake by peripheral tissues, thereby supporting sustained physical and mental activity.
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