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Endoxifen Levels

Meaning

Endoxifen Levels refer to the precisely quantifiable concentration of the potent, active metabolite, 4-hydroxy-N-desmethyl-tamoxifen, circulating in a patient’s systemic bloodstream. This specific metabolite is the primary agent responsible for the therapeutic anti-estrogenic action of the prodrug tamoxifen, a widely used selective estrogen receptor modulator. Measuring these levels is an essential component of therapeutic drug monitoring, ensuring that a patient achieves the minimum effective concentration required for optimal clinical benefit.