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Endotoxin Load Mitigation

Meaning

Endotoxin Load Mitigation is the clinical and nutritional strategy focused on reducing the systemic circulation of bacterial lipopolysaccharide (LPS), an inflammatory molecule released from the cell walls of gram-negative bacteria, primarily in the gut. High levels of circulating LPS, or endotoxins, constitute a chronic inflammatory burden that can significantly impair metabolic and hormonal signaling throughout the body. Successful mitigation aims to lower this systemic inflammatory signal, thereby supporting overall endocrine and metabolic function.