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Endothelial Cell Proliferation

Meaning

Endothelial Cell Proliferation is the biological process involving the rapid increase in the number of endothelial cells, which form the single-cell layer lining the interior surface of blood vessels, known as the endothelium. This proliferation is a fundamental step in angiogenesis, the formation of new blood vessels, and is essential for wound healing, tissue regeneration, and adequate blood flow. Maintaining a healthy rate of proliferation is vital for cardiovascular integrity and for supplying oxygen and nutrients to all tissues. Dysregulated proliferation can contribute to pathological states, including atherosclerosis or tumor growth.