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Endogenous Testosterone Influence

Meaning

The physiological impact and complex regulatory actions exerted by testosterone that is naturally synthesized and secreted by an individual’s own endocrine glands, primarily the testes in males and the adrenal glands and ovaries in females. This internal influence is mechanistically distinct from exogenous administration and is critical for maintaining muscle mass, bone density, libido, erythropoiesis, and essential cognitive function across the lifespan. The magnitude of this influence is highly dependent on the circulating free and total testosterone levels.