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Endogenous Signal Amplification

Meaning

Endogenous signal amplification is the physiological process by which a small concentration of an internally produced signaling molecule, such as a hormone or neurotransmitter, generates a disproportionately large and robust cellular response. This mechanism is critical for the efficient and rapid communication within the endocrine and nervous systems, allowing a minimal initial stimulus to elicit a significant systemic effect. It ensures that the body can quickly and effectively respond to physiological changes, such as stress or nutrient availability.