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Endogenous Production Markers

Meaning

Endogenous Production Markers are specific biochemical substances or metabolites measured in biological fluids, such as blood or urine, that serve as quantifiable indicators of the body’s own internal synthesis rate of a particular compound, often a hormone. These markers provide crucial diagnostic information by reflecting the functional capacity of an endocrine gland or metabolic pathway, offering a more nuanced view than simply measuring the final hormone concentration. In clinical practice, they are essential for distinguishing between naturally diminished hormone output and issues related to peripheral metabolism or exogenous substance use.