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Endogenous Peptide Signaling

Meaning

Endogenous Peptide Signaling describes the natural process by which short chains of amino acids, synthesized within the body, act as highly specific ligands to transmit regulatory information between cells and tissues. These signaling peptides, which include hormones like insulin and various growth factors, bind to specific cell surface receptors to modulate physiological processes ranging from appetite regulation to cellular growth and repair. The integrity of this signaling network is fundamental for maintaining homeostatic balance and coordinating complex biological functions. Disruptions in this system are implicated in numerous metabolic and age-related disorders.