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Endogenous Melatonin

Meaning

Endogenous Melatonin is the hormone naturally produced and secreted primarily by the pineal gland in the brain, playing a critical role as the body’s principal regulator of the circadian rhythm. This indoleamine hormone signals the onset of biological night, thereby facilitating the initiation and maintenance of sleep. It is an essential component of the neuroendocrine system, linking environmental light cues to the body’s internal timing mechanisms. The level of endogenous melatonin is a crucial biomarker for assessing circadian health.