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Endogenous Hormone Synthesis Modulation

Meaning

Endogenous Hormone Synthesis Modulation is the clinical approach involving the deliberate, targeted adjustment of the body’s natural production rates of its own hormones, as opposed to relying solely on the administration of exogenous replacement hormones. Modulation seeks to optimize the complex, rate-limiting enzymatic pathways that convert precursor molecules, such as cholesterol and pregnenolone, into active steroid and peptide hormones. This strategy respects the inherent wisdom and regulatory capacity of the human endocrine system, promoting a balanced, self-regulating hormonal environment that is more resilient and adaptable.