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Endogenous Hormonal Fluctuations

Meaning

Endogenous hormonal fluctuations refer to the natural, cyclical, and pulsatile variations in the concentration of hormones that are synthesized and secreted from within the body’s own endocrine glands. These oscillations are essential for maintaining physiological homeostasis, governing everything from the menstrual cycle and cortisol diurnal variation to the nocturnal release of growth hormone. Understanding the precise timing and amplitude of these internal rhythms is paramount for personalized hormonal health, as deviations from established norms often signal underlying dysfunction or disease pathology. Clinical assessment of these fluctuations requires dynamic testing protocols, not just single point-in-time measurements.