Endogenous Growth Factors are naturally produced signaling proteins, such as IGF-1 or various cytokines, synthesized within the body to regulate cellular proliferation, differentiation, and survival.
Origin
The term is rooted in cellular biology and endocrinology, highlighting factors generated internally to manage tissue maintenance and repair.
Mechanism
These factors operate by binding to specific cell surface receptors, initiating intracellular phosphorylation cascades that ultimately influence DNA transcription and protein synthesis necessary for growth.
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