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Endogenous Clock Synchronization

Meaning

Endogenous Clock Synchronization is the critical physiological process by which the body’s internal master circadian pacemaker, the SCN, aligns its timing with the external 24-hour day-night cycle, ensuring optimal temporal coordination of all peripheral clocks. This synchronization, also known as entrainment, is essential for regulating the precise timing of hormone release, metabolic function, and the sleep-wake cycle. A failure in this alignment, termed chronodisruption, can lead to widespread endocrine and metabolic dysfunction. This is a foundational requirement for health and vitality.