What is the Origin of Endogenous Antioxidant?

The term is derived from "endogenous," from the Greek endon (within) and genos (producing), meaning originating from within an organism, and "antioxidant," meaning against oxidation. The study of these compounds grew out of research into free radical chemistry and the biochemical mechanisms of aging and cellular pathology. This area of study is foundational to longevity science.

What is the Mechanism of Endogenous Antioxidant?

Endogenous antioxidants operate through various biochemical pathways, often involving the donation of an electron to a free radical to stabilize it, thus halting the destructive chain reaction of oxidation. Enzymatic antioxidants, like superoxide dismutase, convert reactive species into less harmful molecules, which are then further processed. Non-enzymatic antioxidants, such as uric acid, directly scavenge free radicals within the cellular environment.

Endogenous Antioxidant ∞ Area

Endogenous Antioxidant

Meaning

An endogenous antioxidant is a molecule naturally produced within the human body that functions to neutralize reactive oxygen species (ROS) and prevent oxidative damage to cellular components. These internally generated compounds, such as glutathione, catalase, and superoxide dismutase, are essential for maintaining cellular integrity and protecting DNA, proteins, and lipids from free radical stress. They form the body’s primary defense system against chronic cellular degradation.