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Endocrine-Vascular Axis

Meaning

The Endocrine-Vascular Axis represents the integrated regulatory system involving the endocrine glands and the vascular network, highlighting the profound influence of hormones on blood vessel structure and function. This communication pathway governs critical vascular processes, including endothelial function, vascular tone, angiogenesis, and the maintenance of blood pressure. Key hormonal mediators in this axis include sex steroids, glucocorticoids, thyroid hormones, and components of the Renin-Angiotensin-Aldosterone System (RAAS). Imbalances within this axis are central to the pathogenesis of numerous cardiovascular diseases, such as hypertension and atherosclerosis.