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Endocrine System Microbiome

Meaning

This term refers to the profound, reciprocal influence between the human endocrine system—the network of glands that secrete hormones—and the collective microbial community, primarily residing in the gut. The microbiome metabolizes and regulates circulating hormones, including estrogens and androgens, and produces signaling molecules that directly affect host hormone production and receptor sensitivity. This intricate relationship is critical for maintaining metabolic health, reproductive function, and stress response. Dysbiosis in this community can directly contribute to hormonal dysregulation.