Endocrine System Decline

Meaning

Endocrine System Decline refers to the gradual, age-associated reduction in the functional capacity and regulatory precision of the body’s hormone-producing glands, leading to measurable changes in circulating hormone levels and target tissue responsiveness. This physiological attenuation impacts numerous homeostatic processes, including metabolism, reproductive function, and stress adaptation, often contributing to the clinical presentation of aging. It is a complex process influenced by genetic factors, chronic inflammation, and environmental stressors.

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