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Endocrine Signaling Phase Alignment

Meaning

Endocrine signaling phase alignment refers to the state where the rhythmic secretion and sensitivity of multiple key hormones are precisely synchronized with each other and with the body’s central circadian pacemaker. Achieving this alignment ensures that hormonal actions, such as insulin release, cortisol pulses, and growth hormone secretion, occur at their biologically optimal times relative to the sleep-wake cycle and feeding schedule. This coordinated timing is essential for maximizing metabolic efficiency and promoting long-term health.