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Endocrine Signal Transduction

Meaning

Endocrine signal transduction is the complex intracellular process by which a hormonal message, initiated by a circulating hormone binding to its specific receptor on a target cell, is converted into a biological response within that cell. This molecular cascade is the fundamental mechanism of action for all hormones, dictating how an endocrine signal translates into changes in gene expression, enzyme activity, or cellular behavior. Understanding the fidelity and efficiency of this transduction pathway is crucial for diagnosing and treating conditions related to hormone resistance, such as Type 2 diabetes or certain forms of thyroid dysfunction. This process ensures systemic communication across vast distances within the human body.