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Endocrine Potency

Meaning

Endocrine potency quantifies the intrinsic biological strength and signaling capacity of a hormone or an exogenous compound to elicit a specific physiological response within the endocrine system. It is a measure of the concentration required to produce a maximal or half-maximal effect at the target receptor site, reflecting both receptor affinity and post-receptor signaling efficiency. A compound with high endocrine potency requires a smaller dose to achieve the desired clinical outcome, minimizing systemic exposure and potential off-target effects. Understanding this metric is crucial for precise therapeutic dosing and maximizing the benefit-to-risk ratio in hormonal interventions.