A clinically defined, personalized spectrum of hormone concentrations and rhythmic patterns that supports an individual’s optimal physical, cognitive, and metabolic function. This range extends beyond the standard laboratory reference values, focusing instead on the levels associated with peak physiological vitality and resilience. Deviations from this optimal range often correlate with subtle yet impactful health and performance deficits.
Origin
The term combines ‘Endocrine,’ relating to the system of hormone-secreting glands, with ‘Performance Range,’ a concept borrowed from engineering and sports medicine. It reflects a shift in clinical perspective from merely diagnosing deficiency to actively optimizing hormonal signaling for enhanced well-being.
Mechanism
Maintaining hormone levels within this performance range ensures optimal receptor binding and efficient downstream signaling across multiple organ systems. For example, maintaining ideal thyroid hormone levels ensures maximal metabolic rate and energy production, while optimizing sex steroid levels supports mood stability and lean tissue mass. The mechanism relies on precise feedback loops within the hypothalamic-pituitary-adrenal (HPA) and other axes to sustain homeostasis under physiological stress.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.