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Endocrine-Neural Interface

Meaning

The Endocrine-Neural Interface describes the critical anatomical and functional nexus where the body’s hormonal (endocrine) and nervous (neural) systems continuously interact, communicate, and mutually regulate systemic physiology. This interface is most prominently exemplified by the hypothalamic-pituitary axis, forming the central control hub for numerous homeostatic processes, including stress response and reproduction. Understanding this bidirectional communication is fundamental to addressing conditions that involve complex hormonal and neurological dysregulation, such as mood disorders or neurodegenerative changes. It represents the unified, highly integrated command center of human physiology.