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Endocrine-Metabolic Interplay

Meaning

Endocrine-metabolic interplay describes the complex, continuous, and bidirectional communication and functional integration between the body’s hormone-regulating endocrine system and its energy-governing metabolic system. This essential interaction ensures that the body’s energy requirements, nutrient availability, and physiological demands are precisely synchronized to maintain systemic homeostasis. Clinically, disruptions in this interplay are fundamental to the pathophysiology of prevalent conditions such as insulin resistance, obesity, and type 2 diabetes, highlighting its critical relevance to overall longevity and wellness. This holistic view is necessary for effective treatment.