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Endocrine Disruptor Response

Meaning

The Endocrine Disruptor Response describes the body’s integrated physiological and biochemical reaction to exposure to exogenous substances, known as endocrine-disrupting chemicals (EDCs), that specifically interfere with the synthesis, secretion, transport, binding, action, or elimination of natural, endogenous hormones. This response is a critical area of concern in environmental health and endocrinology, as it can lead to profound dysregulation of the entire endocrine system’s delicate balance. The clinical manifestation can range widely from subtle metabolic shifts to overt reproductive or developmental abnormalities.