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Endocrine Disruptor Clearance

Meaning

Endocrine Disruptor Clearance is the critical physiological process by which the body’s detoxification systems metabolize, inactivate, and subsequently eliminate exogenous chemicals that interfere with the synthesis, secretion, transport, or action of endogenous hormones. Effective clearance is absolutely paramount for maintaining systemic endocrine homeostasis and reducing the long-term toxicological burden on sensitive target tissues. This vital detoxification pathway involves complex, multi-stage enzymatic reactions primarily orchestrated by the liver and kidneys.