The scientific discipline focused on how the internal biological timing system, the circadian and other endogenous oscillators, regulates the synthesis, secretion, and action of hormones throughout the body. Understanding this interplay is critical for diagnosing and treating disorders involving rhythmic dysregulation. This field explores the temporal organization of the endocrine system.
Origin
This is a specialized sub-field combining endocrinology with chronobiology, the study of biological rhythms. Its foundation lies in recognizing that hormone action is highly dependent on the time of day or cycle when measured.
Mechanism
The mechanism centers on the suprachiasmatic nucleus (SCN) acting as the master clock, which synchronizes peripheral clocks in endocrine organs like the adrenals and gonads. This synchronization dictates the pulsatile release patterns of hormones, ensuring appropriate receptor presentation and metabolic signaling occurs at the biologically correct time window.
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