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Endocrine Axis Sensitivity

Meaning

Endocrine Axis Sensitivity refers to the degree of responsiveness of the endocrine glands and their target tissues to hormonal signals within a specific regulatory loop, such as the Hypothalamic-Pituitary-Adrenal (HPA) axis. High sensitivity indicates efficient signal transduction, while reduced sensitivity suggests a blunted response, often seen in chronic stress or aging. Optimizing this sensitivity is key to restoring hormonal balance.