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Endocrine Aging

Meaning

Endocrine Aging, clinically termed endocrinosenescence, is the inevitable, gradual decline in the functional capacity and regulatory efficiency of the endocrine system that accompanies advancing chronological age. This pervasive process is characterized by a reduction in the synthesis and secretion of various key hormones, alongside an altered responsiveness of peripheral target tissues to circulating hormone levels. The age-related declines in DHEA, growth hormone, and sex steroids contribute significantly to the overall phenotype of biological aging.