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Enclomiphene Response

Meaning

The Enclomiphene Response describes the specific and predictable physiological and biochemical changes observed in an individual following the therapeutic administration of enclomiphene, which is the purified trans-isomer of clomiphene citrate, functioning as a selective estrogen receptor modulator (SERM). This clinical response is primarily characterized by a significant and targeted increase in the body’s own endogenous testosterone production, which is a key strategy utilized in men with secondary hypogonadism seeking to maintain fertility and natural hormonal rhythmicity. It is recognized as a precise, non-exogenous intervention designed to stimulate the individual’s native Hypothalamic-Pituitary-Gonadal (HPG) axis.