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Enclomiphene Mechanism of Action

Meaning

The precise physiological process by which the pharmaceutical agent enclomiphene citrate, the therapeutically active trans-isomer of clomiphene, exerts its effects within the neuroendocrine system. Enclomiphene functions as a selective estrogen receptor modulator (SERM), acting primarily to stimulate the body’s endogenous production of testosterone in the context of secondary hypogonadism. This targeted mechanism allows for the restoration of a healthy hormonal balance while maintaining testicular function and fertility. Its unique action minimizes the unwanted estrogenic effects often associated with the parent compound.