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Enclomiphene Efficacy

Meaning

Enclomiphene efficacy refers to the demonstrated capacity of the drug enclomiphene citrate, a selective estrogen receptor modulator (SERM), to achieve its desired therapeutic outcome, specifically in the treatment of secondary hypogonadism in men. The primary measure of its efficacy is the drug’s ability to selectively block estrogen receptors in the hypothalamus and pituitary gland, leading to a significant and sustained increase in endogenous testosterone production. This is often achieved without the suppression of spermatogenesis typically associated with exogenous testosterone replacement therapy.