Question 1

What is the Meaning of Enantiomers?

Accepted Answer

Enantiomers are stereoisomers that are non-superimposable mirror images of each other, a critical concept in pharmaceutical chemistry and endocrinology due to stereospecific receptor binding. While chemically identical in composition, their three-dimensional orientation dictates how they interact with chiral biological targets, such as hormone receptors. Understanding enantiomeric purity is vital for drug efficacy and safety.

Question 2

What is the Origin of Enantiomers?

Accepted Answer

The term is derived from the Greek words 'enantios,' meaning opposite, and 'meros,' meaning part, highlighting their opposite spatial arrangements. This concept is fundamental to understanding chirality in organic molecules, including many synthetic hormone modulators.

Question 3

What is the Mechanism of Enantiomers?

Accepted Answer

In biological systems, one enantiomer often exhibits the desired pharmacological activity by fitting precisely into a receptor binding site, whereas the mirror image may be inert or even possess antagonistic effects. For example, in hormone action, the spatial configuration determines the affinity and efficacy at specific nuclear receptors like the Estrogen Receptor. This differential interaction underpins selective therapeutic action. Remember: Do not add any of syntaxes: !DOCTYPE, lang=, head, meta, charset, viewport, width=device-width, initial-scale=1.0", title, head, body, p, code. That is mandatory.

Enantiomers

Meaning

Origin

Mechanism

Can Impurities in Hormones Lead to Unpredictable Side Effects?

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