Question 1

What is the Meaning of EGCG?

Accepted Answer

EGCG is the widely recognized acronym for Epigallocatechin Gallate, a highly bioactive polyphenol and the most prevalent catechin found in green tea leaves. This compound is clinically significant for its potent antioxidant, anti-inflammatory, and potential metabolic regulatory properties. In the wellness domain, it is studied as a nutraceutical agent capable of modulating key cellular longevity and energy pathways.

Question 2

What is the Origin of EGCG?

Accepted Answer

The compound is a natural product of the Camellia sinensis plant, the source of green tea, a beverage with a long history of traditional consumption in Asian cultures for its perceived health benefits. Its chemical structure was elucidated and its specific molecular bioactivity began to be systematically investigated by pharmacologists in the late 20th century.

Question 3

What is the Mechanism of EGCG?

Accepted Answer

EGCG exerts its biological effects through diverse molecular pathways, including the inhibition of the enzyme catechol-O-methyltransferase (COMT), which extends the half-life of catecholamines and supports thermogenesis. Crucially, it acts as a known modulator of metabolic master regulators like AMP-activated protein kinase (AMPK) and sirtuins, enzymes that link cellular energy status to gene expression. This dual action supports metabolic flexibility and can enhance the endocrine system's response to nutritional signals.

EGCG

Meaning

Origin

Mechanism

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