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Effective Renal Plasma Flow

Meaning

Effective Renal Plasma Flow (ERPF) is a physiological measure that quantifies the volume of blood plasma delivered to the functional renal tissue—the parts of the kidney capable of filtration and secretion—per unit of time. This measurement serves as a critical clinical indicator of renal perfusion and overall kidney function, which is particularly relevant in the hormonal health space as the kidneys play a major role in hormone metabolism and excretion. A reduced ERPF can signal underlying renal disease or significant circulatory compromise, potentially impacting the clearance of endogenous hormones and exogenous therapeutic agents.