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E2: T Ratio

Meaning

The E2: T Ratio represents the calculated relationship between the circulating concentrations of Estradiol (E2), the primary estrogen, and Testosterone (T), the main androgen, in the bloodstream. This metric serves as a vital clinical indicator of the functional balance between the body’s major sex steroid hormones, offering a more nuanced perspective than measuring either hormone in isolation. The ratio is particularly relevant in male health to assess the efficiency of the aromatase enzyme, which converts testosterone into estradiol.