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Dynamic Reference Ranges

Meaning

Dynamic Reference Ranges are clinical laboratory values that move beyond static, population-based statistical norms to integrate and adjust for individual physiological variables such as age, sex, chronobiological timing, and specific health goals. Unlike traditional fixed ranges, these dynamic parameters recognize that the truly optimal concentration of a biomarker is a functional spectrum that changes based on an individual’s unique biological context. Utilizing these individualized ranges is a hallmark of personalized and precision clinical practice.