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Dutasteride Hepatic Steatosis

Meaning

Dutasteride Hepatic Steatosis refers to the clinical observation of liver fat accumulation, commonly known as Non-Alcoholic Fatty Liver Disease, or NAFLD, potentially associated with the use of the dual 5-alpha reductase inhibitor medication, dutasteride. This is a significant metabolic side effect that raises clinical concern, as the medication is prescribed long-term for conditions like benign prostatic hyperplasia and hair loss. The development of hepatic steatosis indicates a dysregulation of lipid metabolism within the liver parenchyma, a process that can be independent of circulating testosterone levels.