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Drug Interaction Studies

Meaning

Drug interaction studies are systematic clinical or in vitro investigations designed to evaluate how the co-administration of one drug affects the pharmacokinetics (absorption, distribution, metabolism, and excretion) or pharmacodynamics (mechanism of action and effect) of another drug. These essential studies aim to identify potential synergistic, additive, or antagonistic effects, or to detect changes in drug exposure that could lead to toxicity or therapeutic failure. In hormonal health, this is crucial for combination therapies where one agent might alter the metabolism of endogenous or exogenous hormones. Comprehensive drug interaction data informs safe prescribing practices and dosing adjustments.