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Drug-Food Interactions

Meaning

Drug-food interactions describe the measurable physiological and biochemical effects that specific foods, beverages, or dietary components can have on the pharmacokinetics or pharmacodynamics of a pharmaceutical agent, including hormone therapies. These interactions can significantly alter the drug’s absorption rate, distribution volume, metabolism by hepatic enzymes, or elimination half-life, leading to sub-therapeutic levels or potentially toxic concentrations. Clinically, recognizing these interactions is crucial for optimizing the efficacy and safety of prescribed medications, particularly in endocrinology where precise dosing is critical for maintaining homeostatic balance.