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Dopamine Re-Sensitization

Meaning

Dopamine Re-Sensitization is a neurobiological strategy aimed at restoring the normal density and function of dopamine receptors, particularly D2 receptors, in the brain’s reward and motivation pathways. Chronic overstimulation from highly reinforcing stimuli, such as excessive screen use, hyper-palatable foods, or certain substances, can lead to receptor downregulation and a state of hedonic adaptation. This process is designed to lower the baseline threshold required for dopamine release, allowing for greater enjoyment and motivation from natural, healthy stimuli. It is a critical intervention for individuals experiencing apathy or anhedonia linked to hormonal and neurochemical imbalance.