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Dopamine Modulation

Meaning

Dopamine modulation is the clinical or behavioral process of regulating the synthesis, release, receptor binding, and reuptake of dopamine, a critical catecholamine neurotransmitter in the central nervous system. This regulation is essential for maintaining optimal function in brain pathways associated with reward, motivation, executive function, and motor control. Effective modulation aims to prevent both deficiency states, which can lead to anhedonia and poor focus, and excessive signaling, which can contribute to impulsivity or addiction.