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Dopamine Loops

Meaning

The interconnected neural circuits, primarily involving the mesolimbic and mesocortical pathways, that utilize the neurotransmitter dopamine to regulate motivation, reward-seeking behavior, pleasure, and executive function. These loops are central to the body’s internal drive system, governing the anticipation and pursuit of goals, and are critically influenced by various neurohormones. Dysregulation in these circuits can lead to issues with addiction, apathy, and impaired decision-making. Optimal function is essential for goal-directed action.